Hendra virus and Nipah virus animal vaccines
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چکیده
منابع مشابه
Hendra and Nipah Virus Diseases
Hendra virus (HeV) and Nipah virus (NiV) emerged in the last decade of the twentieth century as the causes of outbreaks of respiratory and neurological disease that infected a number of animal species. In 1994, HeV caused severe respiratory disease and the death of 13 horses and a horse trainer at a stable in Brisbane, Australia. Between September 1998 and April 1999, after spreading unrecognis...
متن کاملHendra and Nipah Virus Diseases
Hendra virus (HeV) and Nipah virus (NiV) emerged in the last decade of the twentieth century as the causes of outbreaks of respiratory and neurological disease that infected a number of animal species. In 1994, HeV caused severe respiratory disease and the death of 13 horses and a horse trainer at a stable in Brisbane, Australia. Between September 1998 and April 1999, after spreading unrecognis...
متن کاملPathogenesis of Hendra and Nipah virus infection in humans.
Hendra virus (HeV) and Nipah virus (NiV) are emerging zoonotic viruses that cause severe and often lethal respiratory illness and encephalitis in humans. Henipaviruses can infect a wide range of species and human-to-human transmission has been observed for NiV. While the exact route of transmission in humans is not known, experimental infection in different animal species suggests that infectio...
متن کاملEphrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus.
Hendra virus (HeV) and Nipah virus (NiV) belong to the genus Henipavirus of the family Paramyxoviridae and are unique in that they exhibit a broad species tropism and cause fatal disease in both animals and humans. They infect cells through a pH-independent membrane fusion process mediated by their fusion and attachment glycoproteins. Previously, we demonstrated identical cell fusion tropisms f...
متن کاملNovel Functions of Hendra Virus G N-Glycans and Comparisons to Nipah Virus.
UNLABELLED Hendra virus (HeV) and Nipah virus (NiV) are reportedly the most deadly pathogens within the Paramyxoviridae family. These two viruses bind the cellular entry receptors ephrin B2 and/or ephrin B3 via the viral attachment glycoprotein G, and the concerted efforts of G and the viral fusion glycoprotein F result in membrane fusion. Membrane fusion is essential for viral entry into host ...
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ژورنال
عنوان ژورنال: Vaccine
سال: 2016
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2016.03.075